Banca de QUALIFICAÇÃO: GESSIANE PEREIRA DA SILVA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : GESSIANE PEREIRA DA SILVA
DATE: 27/09/2021
TIME: 19:30
LOCAL: Google meet (https://meet.google.com/jez-nkcu-koy?hs=122&authuser=0)
TITLE:

MONITORING SENSCENCE AND STRESS LEVELS IN NEOTROPICAL PRIMATES

KEY WORDS:

Wild animal welfare; Adrenal steroids; DHEAS.

PAGES: 75
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Reprodução Animal
SPECIALTY: Ginecologia e Andrologia Animal
SUMMARY:

Monitoring stress in the wild or captive animals is an important tool for animal conservation and species reproduction. Due to the limitations of the isolated use of glucocorticoids (GCs) in the assessment of stress, currently, the ratio of GCs production with dehydroepiandrosterone sulfate (DHEAS), a steroid hormone that has anti-GCs activity, has been chosen. Furthermore, the relationship between DHEAS concentration and age has been observed, in which there is an increase in DHEAS before puberty in great apes and in humans, but a linear decrease of this hormone with age in catarrhines primates. In platyrrhines primates the DHEAS secretion pattern is still unknown. Thus, we aim to analyze the pattern of DHEAS secretion with age and the association of the GC/DHEAS ratio with stress-related factors in three platyrrhines primate (Alouatta sp, Aotus sp. and Sapajus sp.), in different age groups, of captivity. 250 sample fazes and blood were collected, performed parasitological examinations, hematology, serum biochemistry and abdominal ultrasonography. A validation of hormonal assays of DHEAS and cortisol was performed, based on the pharmacological challenge with DHEA and adrenocorticotropic hormone (ACTH) in the three species, and the analysis of feces of pregnant females A. caraya. The results of laboratory tests showed clinical changes in the animals. An abdominal ultrasound will attest to health and observe small changes in the animals. The validation of the assays was certified by parallelism and accuracy tests, and by the effect of gestation observed as an increase in the concentration of DHEAS. The previous results allowed to extend the study of the GC/DHEAS ratio in the assessment of stress, and the comparison of the concentration of DHEAS with catarrhines primate to establish the possible effects of the hormone on the senescence and evolution of primate species.

BANKING MEMBERS:
Interno - 388501 - WASHINGTON LUIZ ASSUNCAO PEREIRA
Interno - 748.420.568-00 - WILTER RICARDO RUSSIANO VICENTE - UNESP
Externa ao Programa - 805.474.272-04 - RAFAELA SAYURI CICALISE TAKESHITA - KYOTO-U
Externo à Instituição - RODRIGO HIDALGO FRICIELLO TEIXEIRA
Externa à Instituição - TATIANA KUGELMEIER - Fiocruz - RJ
Externo à Instituição - RAFAEL DOS SANTOS DE ANDRADE - UFRA
Externa à Instituição - MARIA VIVINA BARROS MONTEIRO - UFPA