NUTRITION AND PRODUCTION OF PILOCARPINE IN JABORANDI PLANTS
Plant nutrition. P. microphyllus. Pilocarpine.
The species of the genus Pilocarpus, also known as Jaborandi, are plants that produce the substance pilocarpine (alkaloid), abundantly used in the pharmaceutical industry. In Pará, the species Pilocarpus microphyllus is the most important, as it has the highest concentration of pilocarpine, and can be found around of the Carajás National Forest (FLONA). Its cultivation in planted areas is still complex, since the main difficulty is to understand the factors that favor the greater production of this substance, also permeating nutritional aspects still poorly understood. In this context, this research aims to evaluate the nutrients that influence pilocarpine production in jaborandi plants. For this, two trials were carried out, in the first one, P. microphyllus plants and soil were collected in areas of the Carajás National Forest, where soil chemical parameters and foliar nutrient contents were correlated with pilocarpine production. And in the second trial, nitrogen concentrations were evaluated in the nutritional status, physiological parameters, growth and pilocarpine content in jaborandi seedlings. The results found in the first chapter show that, through multivariate analysis, the model that best predicted pilocarpine production was composed of leaf N, leaf Mg, soil Fe (positive predictors), soil S and leaf P (negative predictors). As for the effects of nitrogen concentrations, the preliminary results point to a greater accumulation of dry mass at the highest applied concentrations, such as an increase in growth parameters. The nutrient contents showed different behaviors in the different parts of the plant, and for the physiological parameters, the intermediate doses provided the best responses.